My research investigates the neural bases of human eternal-term memory. I use functional neuroimaging (fMRI), experimental psychology, neuropsychological studies of amnesic patients, and studies of aging and dementia to enquire how the neural systems supporting these various types of memory operate and interact. Peculiar emphasis is placed connected discernment the human hippocampus and other components of the medial temporal lobe. Memory can be subdivided into a variety of types (implicit vs. explicit, declarative vs. nondeclarative) that can be tested in a variety of ways (remember vs. recognition, reminiscence vs. familiarity) that depend on a variety of computations (pattern breakup vs. pattern closing) and rely on a miscellanea of brain structures (hippocampus, MTL, prefrontal cortex, striatum). To make up matters even more absorbing, most of these divisions are not in truth polarized, but instead, there are interactions and a kind of spectrum that underlies the two extremes. Much of the research in our laboratory tries to button these boundaries, to evaluate non just the extremes, just the sunglasses of gray in between. As an undergraduate and later in postgraduate school, where I studied with Jay McClelland, I learned how to suppose just about the brain's cognitive abilities in terms of computations. I designed procedure models to evaluate the cognitive performance that we detect in humans. I no longer do much of the modeling myself any longer, just my thinking is still very much motivated by computational models of the brain and much of the research in my lab is focused on testing some of the hypotheses plagiaristic from these models. The research in my laboratory is largely derived from two sources: demeanor and MRI. In humans, the primary quill read-out of memory is still behavioral performance, so this is still the above all and most important variable that we return to. However, deportment doesn't tell United States anything about the brain, so to address where and how this behavior is copied, we use MRI. There are many techniques that can be utilized with MRI: functional, structural, diffusion-tensor imaging, resting-state and functional connectivity, among others. In the Stark laboratory, we try to non only apply these techniques to our questions of occupy, but push them further, germinate them in novel shipway, and create spic-and-span methods to address doddering problems. The theatre of operations of cognitive neuroscience grew out of the observation that individuals with brain damage exhibited changes in behavior. As a field of study, we still rely along these observations, some to slough short on the underlying mechanisms and brain regions involved in a behavior, and in an effort to better understand disease and disorders. In my postdoctoral fellowship with Larry Squire, I tested amnesic patients to do questions all but memory behavior following harm to the Hippocampus and medial worldly lobes. In the Stark lab, we forthwith work with several some other populations to speech different questions. Our main area of focus in recent years has been on aging and dissociating those behavioural and neural changes associated with aging from those associated with the early memory impairments observed in Alzheimer's disease. In addition, we are interested in both behavioral and neural changes joint with individuals with depression, Schizophrenia, and babyhood stress. On the flip broadside, we are also investigating the incredible memories of those individuals with Extremely Superior Autobiographical Storage.
Lab Website
UCI Faculty Profile
what are the two extremes of memory recall ability
Source: https://cnlm.uci.edu/about/craig-stark/
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